Police are appealing for public assistance to locate a man missing from the state’s Hunter region.

Andrew Weatherstone, aged 47, has not been seen or heard from by family and friends since 6pm on Saturday (19 September).

He was reported missing to officers from Newcastle City Police District, who commenced an investigation to locate him.

Police and family hold concern for his welfare due the disappearance being out of character.

Andrew is described as being of Caucasian appearance, about 190cm tall, of medium build, with brown hair, brown eyes and a moustache.

It is believed he is driving a white Toyota Camry sedan, and is known to frequent Newcastle and surrounding suburbs.

Anyone who may have information are urged to contact Newcastle Police Station on (02) 4926 6537 or Crime Stoppers on 1800 333 000.